Associate Professor
Division of Infectious Diseases
Cincinnati Children’s Hospital Medical Center
Department of Pediatrics
University of Cincinnati, College of Medicine
Cincinnati, Ohio, USA
Dr. Tan graduated from Zhongshan (Sun Yat-sen) University in China in 1982 and 1986, receiving his Bachelor’s and Master of Science degrees, respectively. He then completed his graduate training at the University of Muenster in Germany, earning his doctorate in 1997. Dr. Tan spent much of his career at the Cincinnati Children’s Hospital Medical Center, affiliated with the University of Cincinnati, College of Medicine in the USA, starting in 2002. Currently, Dr. Tan is an associate professor at the Cincinnati Children’s Hospital Medical Center. His recent research focuses on virus-host interactions of norovirus, rotavirus, and other viruses through viral receptors and/or host attachment factors, as well as their impacts on viral infection and host susceptibility. He also studies the structural features of noroviral capsids and has generated two norovirus capsid protein-based nanoparticles as research models to study virus-host interactions and as polyvalent nanoplatforms to display antigens from other pathogens for enhanced immunogenicity for novel vaccine development. The Tan lab has generated several pseudovirus nanoparticles displaying various viral neutralizing and protective antigens and evaluated them as promising subunit vaccine candidates against various infectious diseases. Dr. Tan’s publication record includes 140 research papers, four book chapters, and nine patents. Four of his patents have been licensed to pharmaceutical companies for further development. |